BDBM50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine
SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
InChI Key InChIKey=QZUDBNBUXVUHMW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50001884
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptor was evaluated using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: <10nMAssay Description:Antagonist activity at human recombinant 5-HT6 receptor assessed as inhibition of serotonin-induced cAMP accumulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to human cloned 5HT6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]5-LSD from human 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at serotonin human 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced calcium flux after 15 min...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
City University Of New York
Curated by ChEMBL
City University Of New York
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 d...More data for this Ligand-Target Pair